Screening and evaluation of antimicrobial activity of actinomycetes isolated from rhizosphere of Heracleum candicans

The present study deals with isolation and screening of industrially and biotechnologically important strains of actinomycetes species for maximum production of antagonistic and proteolytic activities. Total 8 strains were isolated from rhizospheric soil of medicinal plant Heracleum candicans. Three strains were more effective against the indicator test bacteria and fungal pathogens present in soil. Maximum production of proteolytic activity was shown by MK-1 (24 mm), MK-5 (25 mm) and MK-8 (28 mm). These hyper-producing strains of actinomycetes can be exploited in industries for commercial product formation.