Cytogenetic Studies on Pre Partum Vaginal Prolapse in Murrah Buffaloes

Buffaloes (n=12) with a history of prepartum vaginal prolapse were investigated for cytogenetic studies in order to assess the role of chromosomal abnormalities in prepartum vaginal prolapse. Structural chromosomal abnormalities identifying chromatid gaps, isochromatid breaks and dicentric chromosomes were observed at a frequency of 1.39, 0.15 and 0.62 per cent, respectively. The numerical aberrations such as aneuploidy and polyploidy were 2.17 and 0.46 per cent in prolapse group, whereas, aneuploidy was 0.95 per cent in the control group. Numerical and morphological abnormalities of chromosomes were not found at a significant level but genetic role regarding the etiology of this disease, heritability and repeatability cannot be ruled out. So it depicts a possibility of genetic correlation with this condition which may be highlighted by advanced molecular studies.