The Indian Journal of Field Veterinarians

Open Access
  • Year: 2010
  • Volume: 6
  • Issue: 1

Ulcerogenic Activity of Certain Non-Steroidal Anti-Inflammatory Drugs and Enzymes on Gastric Mucosa of Rats

  • Author:
  • K. S. Misraulia, P. Kaskhedikar
  • Total Page Count: 3
  • DOI:
  • Page Number: 42 to 44

Department of Veterinary Medicine, College of Veterinary Science and A.H., Mhow (M.P.).

Abstract

Effect of administration of aspirin, diclofenac sodium, flurbiprofen, nimesulide, piroxicam, serratiopeptidase and trysin-chymotrysin was evaluated on gastric mucosa for ulceration, if any. The results revealed that nimesulide, serratiopeptidase and trypsin-chymotrypsin have safety profile, while with the remaining drugs the incidence of ulceration was 100 per cent.

Keywords

Ulcerogenic, NSAIDs, Gastric mucosa, Rats