Indian Journal of Health Sciences and Care
  • Year: 2017
  • Volume: 4
  • Issue: 2

Prevalence of Inducible Clindamycin Resistance in Staphylococus aureus Isolates in A Peri-Urban Hospital in Haryana

  • Author:
  • Megha Maheshwari1, Vijay Laxmi Malhotra2,, L. Sumitra Devi3, Shobha Broor4
  • Total Page Count: 5
  • Page Number: 57 to 61

1Associate Professor, Department of Microbiology, Faculty of Medicine and Health Sciences, SGT University, Budhera, Gurgaon

2Assistant Professor, Department of Microbiology, Faculty of Medicine and Health Sciences, SGT University, Budhera, Gurgaon

3Tutor, Department of Microbiology, Faculty of Medicine and Health Sciences, SGT University, Budhera, Gurgaon

4Professor and HOD, Department of Microbiology, Faculty of Medicine and Health Sciences, SGT University, Budhera, Gurgaon

*Corresponding author email id: vijaylaxmimalhotra@yahoo.co.in

Online published on 4 November, 2017.

Abstract

Macrolide-lincosamide-streptogramin B (MLSB) antibiotics especially clindamycin is frequently used to treat skin and soft tissue infections due to methicillin resistant Staphylococcus aureus (MRSA). However, widespread use of these antibiotics has led to an increase in resistance against these antimicrobials especially clindamycin, thus necessitating the need to detect such resistance on routine basis using a simple D test. A total of 130 Staphylococcus aureus isolates were subjected to D test, out of which 12 were found to have inducible clindamycin resistance, of which 7 were MRSA and 5 were MSSA. Clinical laboratories should routinely perform D test to guide clinicians about inducible clindamycin resistance to prevent misuse of antibiotics.

Keywords

Clindamycin, D test, Erythromycin, Inducible, Staphylococcus aureus, Resistance