1Professor & Head, Department of Biochemistry & Medicine, Shri Guru Ram Rai Institute of Medical & Health Science, Patel Nagar, Dehradun (UK)
2MD Resident, Department of Biochemistry & Medicine, Shri Guru Ram Rai Institute of Medical & Health Science, Patel Nagar, Dehradun (UK)
*Corresponding author email id: abhinav5manish@gmail.com
Online published on 15 November, 2018.
The aim of our study was to determine the significance of delta bilirubin in cholestasis and to establish a correlation with liver enzymes.
A prospective study was conducted on patients attending the outpatient department of Medicine of SGRR Medical College Dehradun (UK) over a period of six months from January 2018 to June 2018. A total number of 60 cases and 50 controls in the age group 15–75 years were selected randomly.
5ml of venous blood was collected in sterile tubes from all 110 subjects (60 cases and 50 controls) and were analyzed for serum total bilirubin, direct bilirubin, indirect bilirubin, delta bilirubin, SGPT, SGOT, ALP and GGT.
We observed that in cases of cholestasis there was an increase in the serum levels of delta bilirubin and conjugated bilirubin, ALP, GGT and Transaminases. The data was analyzed statistically and the values were expressed as (Mean±SD) and p-value was found to be highly significant.
We conclude that delta bilirubin plays a significant role in the diagnosis of different types of jaundice specially cholestatic jaundice.
Cholestatic jaundice, Delta bilirubin, GGT, ALP, SGPT
