A Cross-sectional Study for Age and Gender Specific TSH Level Among the Workers of Gauhati Medical College, Guwahati, Assam

The purpose of this study was to estimate the thyroid stimulating hormones among the healthy workers at Gauhati Medical College and to find out any relation between age and mean TSH levels among women.

In this cross-sectional, observational study serum TSH (thyroid stimulating hormone) was estimated among 120 normal individual of 21–60 years in the Department of Physiology at Gauhati Medical College.

The means of TSH measurements between males and females of 21–60 was statistically insignificant with a P value of 0.74. However when TSH levels were compared between women of reproductive age and menopausal women there was significant difference between the two groups p<0.001.

This study reports that males did not have any statistically significantly TSH range compared to females. Also, findings from current study indicates that existing TSH reference intervals do not always reflect the distribution of TSH in different age groups. The use of an age-specific reference range for TSH, especially in those over 45 years old, would avoid people with a serum TSH concentration between the 2.5th and 97.5th percentiles being misclassified as “abnormal.”