The information related to the solute-solvent interaction has been carried out related to thermodynamic properties like activation energy, conductivity, enthalpy entropy etc in the mixture of Ayurvedic Medicine-BALANTKADHA 1 and Methanol. Dielectric relaxation study of BALANTKADHA 1 used in gynaec problems has been carried out at 15°C, 25°C, 35°C and 45°C in the frequency range 10MHz to 20GHz for 11 different concentrations of the system. Time Domain Reflectometry (TDR) Technique in reflection mode has been used to measure Thermodynamic parameters viz activation energy, conductivity, enthalpy entropy etc.Further, Fourier transforms and least square fit method has been used to obtain Thermodynamic parameters. With change in concentration and temperature, the systematic changes in Thermodynamic parameters are observed.