Regulatory effect of some plant extracts on the growth of dermatophytic fungi

Antidermatophytic activity of water extract, methanol extract, free and bound flavonoids of different parts of Brassica campestris, Trigonella foenum-graecum, Pisum sativum and Camellia sinensis were evaluated against four dermatophytes, namely Trichophyton rubrum, T. simii, T. terrestre and Chrysosporium indicum in vitro conditions. The results were compared with standard antimycotic drug griseofulvin/ketoconazole. Brassica-flowers showed excellent antidermatophytic properties as compared to other plant parts. Among all the extracts tested, free and bound flavonoid fractions showed greater fungicidal peroperties. Maximum zone of inhibition was recorded in the presence of free flavonoid fraction of Brassica-flowers against T. rubrum. T. terrestre was found to be most susceptible fungus for all the extracts tested.