Indian Journal of Mednodent and Allied Sciences
Open Access
  • Year: 2015
  • Volume: 3
  • Issue: 1

Genetic Syndromes Associated with Cleft Lip and Palate – A Review

1Assistant Professor, Oral Pathology and Microbiology, KGMU, Lucknow, Uttar Pradesh, India

2Reader, Department of Oral Medicine and Radiology, Teerthankar Mahaveer Dental College and Research Centre, Moradabad

3Professor and Head, Department of Oral pathology and Microbiology, Mahe Institute of Dental Sciences, Puducherry

4Senior Resident, Oral Pathology FODS, KGMU, Lucknow, Uttar Pradesh, India

*Corresponding author email id: diksh18@yahoo.com

Online published on 1 October, 2015.

Abstract

Several syndromes are associated with cleft lip and cleft palate. Apart from the several syndromes reported in cleft lip and palate, syndromes require special attention, which are certain Velocardiofacial syndrome, Van der Woude syndrome (VWS), Stickler syndrome. Van der Woude, Foetal alcohol syndrome, Holzgreve syndrome, Marfan syndrome, Myotonic dystrophy, Klippel–Feil syndrome, Patau syndrome, Potter sequence and Pierre Robin sequence are also some of the syndromes which have been associated with cleft lip and palate. Certain measures such as multidisciplinary approach and family counselling may prove to be beneficial to treat cleft lip and palate.

Keywords

Genetic, Syndrome, Velocardiofacial syndrome, Pierre Robin syndrome Marfan syndrome, Multidisciplinary, Genetics of cleft lip and cleft