International Journal of Medical and Dental Science
  • Year: 2012
  • Volume: 1
  • Issue: 1

Tissue Engineering in Oral & Maxillofacial Surgery

  • Author:
  • A Ahuja1, SM Kotrashetti2, U Sethi3, V Singh4, V Jain5
  • Total Page Count: 9
  • Page Number: 14 to 22

1Reader, Dept of Oral & Maxillofacial Surgery, ITS Dental Callege, Haspital & Research Centre, Greater Naida, U.P, India

2Prof & Head, Dept of Oral & Maxillofacial Surgery, KLE's Institute of Dental Sciences Belgaum, Karnataka, India

3Reader, Dept of Oral Medicine & Radiology, ITS Dental College, Hospital & Research Centre, Greater Naida, U.P, India

4Dept of Oral & Maxillofacial Surgery, ITS Dental College, Hospital & Research Centre, Greater Naida, U.P, India

5Prof & Head, Dept of Oral Medicine & Radiology, ITS Dental College, Hospital & Research Centre, Greater Naida, U.P, India

Abstract

A recent innovation in dentistry is the preparation and use of platelet rich plasma, a concentration of platelets and growth factors found in platelets, These polypeptide growth factors as well as other bioactive substances are released from platelets upon activation, which playa pivotal role in initiating and sustaining wound healing and tissue repair mechanism, In order to improve wound healing and bone regeneration, attempts were made to increase the concentration of wound healing initiating factors in the form of platelet concentrate. Platelet derived polypeptide growth factors as well as other bioactive substances are released from platelet upon activation which plays a pivotal role in initiating and sustaining wound healing and tissue repair mechanism, This article is an attempt to highlight the uses of Platelet rich plasma (PRP) in Oral & Maxillofacial Surgery and the preparation of PRP gel in the immediate preoperative period in a laboratory centrifuge.

Keywords

Tissue engineering, Platelet gel, Bone grafting, Maxillofacial surgery