International Journal of Medical and Dental Sciences
  • Year: 2013
  • Volume: 2
  • Issue: 2

Malignant mixed germ cell ovarian tumor in pregnant female

  • Author:
  • Sarbhjit Kaur1,, Vijay Kumar Bodal2, Manjit Singh Bal2, Ranjeev Bhagat2, Nishit Gupta2
  • Total Page Count: 6
  • Page Number: 233 to 238

1Gynecology & Obstetrics, Government Medical College, Patiala, Punjab, India

2Pathology, Government Medical College, Patiala, Punjab, India

*Correspondence to: Dr Sarbhjit Kaur, 91-9814109013, Email: Kaursarbhjit13@gmail.com

Online published on 5 July, 2013.

Abstract

Ovarian germ cell tumours comprise approximately 15% to 20% of all ovarian neoplasms. In pregnant females, its incidence is very low. They arise from primordial germ cells derived from the embryonal gonad. Malignant germ cell tumours comprise less than 5% of all ovarian neoplasms. Most malignant ovarian neoplasms in pregnant women are at early stages and are associated with good prognosis both for the mother and for the neonate. Histologic subtypes and prognosis do not differ from tumors not associated with pregnancy. Careful initial surgery with adequate staging biopsies followed by combination chemotherapy can greatly improve the prognosis of these patients. We present a case of malignant mixed germ cell tumor in a pregnant female who presented with abdominal mass after delivering a normal child. Histological and biochemical tumour markers confirmed it to be malignant mixed germ cell tumor.

Keywords

Malignant mixed germ cell tumour, choriocarcinoma, pregnancy