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Three tricyclic ring system, pyridazino [6,1-b]quinazolin-10-ones, benzimidazolo-pyridazine thione, and 1,2,4-benzotriazino-pyridazinethione combined with imidazo-[1,2-b] -pyridazinethione, 1,2,4- triazolo[4,3-b]pyridazine-thione derivatives were produced beginning from 6-chloropyridazin3-(2H)- thione. Some disulfide and sulphide derivatives were also produced. The antibacterial activity of the produced compounds was investigated. Some of these chemicals feature a strong reaction against grampositive and gram-negative bacteria as well as fungus.
Pyridazino, Chemical, Bacteria, Chloropyridazin