Bacteriological profile and antibiogram of urinary tract infections at a tertiary care hospital

A prospective laboratory based observational study collaborating with medicine, surgery, paediatrics, nephrology, urology, obstetrics & gynaecology and STD departments was carried out over a period of one year with 500 patients suffering from UTI, which included 49% of males and 51% of females. Among the 500 patients, significant bacteriuria was detected in 150 patients that constitute 30% of the sample tested. The highest incidence of urinary tract infection (UTI) 41.3% was recorded in paediatric age group followed by reproductive age group (33.3%). In this study, 129 Gram Negative Bacilli and 21 Gram Positive Cocci were isolated among which, E. coli (57%) was the commonest organism followed by Klebsiella spp (20%). In addition, presence of Pseudomonas aeruginosa (3%), Proteus (2%), Enterobacter (1.35%) and Citrobacter (1.35%) and Acinetobacter (2%) were also detected from the test samples. Among the Gram Positive cocci, 7% were CONS, 5% were Staphylococcus aureus and 1.3% were Enterococcus faecalis. All the Gram negative bacilli were mostly found sensitive to Imepenam (100%) whereas, the Gram positive cocci were sensitive to Vancomycin (100%) followed by Amikacin (84%), Levofloxacin (83%), Cefipime (81%), Cefoxitin (76%) and Nitrofurantoin (61%). Ampicillin and Co-trimoxazole were highly resistant showed only 11% and 13% sensitivity. Cephlosporins, Nalidixic acid and Norfloxacin were resistant to all the isolated pathogen by 50% and more.