Periampullary Carcinoma with Skull Metastasis: A rare case report

Periampullary cancer consist of pancreatic cancer, carcinoma of ampulla of vater, distal common bile duct and duodenum. With the use of multimodality treatment, the prognosis of periampullary carcinoma has been improved. Skull (calvarium) metastasis is uncommon presentation. Only few cases of periampullary carcinoma with skull metastasis are available in English literature. Although rare, metastatic periampullary adenocarcinoma should be considered as a differential diagnosis in patients presenting with abnormal scalp swelling and tenderness. We reported a case of 48 year old female who presented with lytic expansile bony lesion with associated soft tissue mass in left parietal region with no neurological defecit 18 months after the whipples procedure.