Cephalosporin resistance: Challenges in providing appropriate and effective treatment protocols

Empiric therapy is designed to target the microbes that are likely to exist. Appropriate choice of empiric therapy, helps limit the antibiotic consumption and decreases morbidity and mortality. Cephalosporins have often been the mainstay of these protocols. In the present study, overall resistance to antibiotics was 48.69%. Resistance to fourth generation cephalosporins ran parallel to that of third generation cephalosporins. Temporary stoppage or limiting the use of cephalosporins is indicated.