1Head of the Laboratory of Morphology, Doctor of Biological Sciences, Professor, Russian Ilizarov Scientific Center Restorative Traumatology and Orthopaedics (RISC RTO), Kurgan, Russia
2Head of Department of Pathology, Izhevsk State Medical Academy, Doctor of Medical Science, Professor, Russia
3A Senior Researcher, Laboratory of Purulent Osteology and Limb Defect Filling, RISC RTO, Candidate of Veterinary Sciences, Russia
4Head, Department of Orthopaedics, RISC RTO, Candidate of Medical Sciences, Russia
5A Researcher, Department of Orthopaedics, RISC RTO, Candidate of Medical Sciences, Russia
*Corresponding author email: kirnik@list.ru
Online published on 29 July, 2015.
The amage or loss of articular cartilage is costly medical problem. The purpose of this work morphological analysis of reparative chondrogenesis when implanted in the area of the knee joint cartilage of granulated mineralized bone matrix.
The characteristic features of the knee cartilage regeneration studied experimentally in pubertal Wistar rats after modeling a marginal perforated defect and implantation of granulated mineralized bone matrix obtained according to original technology without heat and demineralizing processing into the injury zone.
This biomaterial established to have pronounced chondro-and osteoinductive properties, and to provide prolonged activation of reparative process, accelerated organotypical remodeling and restoration of the articular cartilage injured.
The data obtained demonstrate the efficacy of MBM in clinical practice for the treatment of diseases and injuries of the articular cartilage.
Articular cartilage, The mineral component of bone matrix, Implantation, Reparative chondrogenesis
