1Assistant Professor, Department of Physiology, Akash institute of medical sciences and Research centre, Banglore, Karnataka
2Professor & HOD, Department of Physiology, Thanjavur medical college, Thanjavur, Tamil Nadu
3Associate consultant, Neurology, Sakra world hospital, Banglore, Karnataka
*Corresponding author: Arrthy S Assistant Professor, Department of Physiology, Akash institute of medical sciences and Research centre, Banglore, Karnataka E-mail: drs.arrthy@yahoo.com
Online published on 27 October, 2015.
Cranial neuropathy is one of the common late complications of Diabetes Mellitus(DM), including distal symmetric sensory polyneuropathy and peripheral neuropathy(PN). Though many studies support the involvement of Cranial nerves III, VI and VII in diabetic patients, little was known about the involvement of II & VIII nerve. The goal of this study was to evaluate the involvement of optic nerve and vestibulocochlear nerve using Visual Evoked potential (VEP) and Brainstem Auditary Evoked Potential (BAEP).
Forty patients with 8 to 12 years duration of type 2 DM in 40 to 60 years age group (Group1) were selected from diabetic outpatient department in Thanjavur medical college hospital and compared with control group (Group 2) who were normal subjects and was age and sex matched. Physical examination and laboratory investigations including fasting glucose, renal functions were done in addition to VEP & BAEP for all groups. P100 latency using VEP and bilateral inter-peak latency IPL I-III, IPL III-V & IPL I-V using BAEP was evaluated and and analyzed for the study group and control group.
VEP P100 latency and BAEP bilateral inter-peak latency IPL I-III, IPL III-V & IPL I-V were prolonged in the study group compared to control group.
This study concluded the involvement of optic and vestibulocochlear nerve in type 2 DM as the latency was prolonged.
Visual Evoked Potential, Brainstem Auditory Evoked Potential, Diabetes Mellitus, Inter Peak Latency
