Investigating the influence of local antiseptics on the level of urinary tract infection (UTI) among patients undergoing transrectalbiopsy of prostate

Transrectal ultrasound guided biopsy of the prostate is the most common modality used to diagnose prostate cancer. The main complication of this modality is prostatitis. The purpose of this study is to determine the effect of simple use of suppository povidone-iodine on infectious complications after transrectal ultrasonography-guided biopsy of the prostate. In a randomized clinical trial, 300 patients are included and received antibiotic prophylaxis. Among them, 150 patients received povidone-iodine suppository five minutes prior to biopsy (group 1) and 150 patients did not (group 2). Infectious complications were compared in two groups. Urinary tracts infection were not detected in the rectal preparation group (Group 1) and developed in 13 cases (8.8%) in the non-rectal preparation group (Group 2) (odds ratio=0.912; P<0.001). Prostatitis was not detected in the rectal preparation group (Group 1) and developed in 13 cases (8.8%) in the non-rectal preparation group (Group 2) (odds ratio=0.912; P<0.001). Povidone-iodine into the rectum and decreased the bacterial colony count. Simple use of povidone-iodine suppository before prostate biopsy minimizes the risk of infectious complications.