International Journal of Medical Research & Health Sciences
  • Year: 2016
  • Volume: 5
  • Issue: 4

Sero-epidemiology and risk factors of hepatitis E among pregnant women in Tabriz, Iran

  • Author:
  • Maedeh Alizadeh1, Mandana Rafeey2, Mohammad Asghari Jafarabadi3, Simin Taghavi4, Manizheh Sayyah-Melli5, Heydarali Esmaili6
  • Total Page Count: 4
  • Page Number: 224 to 227

1M.Sc. of Infant Nursing, Maragheh University of Medical science, Maragheh, Iran

2Professore of Pediatric Gastroenterology, MD. Liver and gastrointestinal research center, Tabriz University of Medical Sciences, Tabriz, Iran

3Assistant Professor of Biostatistics, Research Center for Medical Education, and Department of Statistics and Epidemiology, School of Health and Nutrition, Tabriz University of Medical Sciences, Tabriz, Iran

4Associated Professor of OB &GYN, MD. Women's Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

5Professor of OB & GYN, Women's Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

6Associated Professor of Anatomical and Clinical, Tabriz University of Medical Sciences, Tabriz, Iran

Online published on 29 September, 2018.

Abstract

Hepatitis E Virus (HEV) in pregnant women is more severe, often leading to fulminates hepatic failure, death in mother, abortion and death of infants. The aim of this study was to determine the Sero-epidemiology and risk factors of anti-HEV IgG antibodies in pregnant women in East Azerbaijan of Iran because the prevalence in Iranian pregnant women is almost unclear. We performed a descriptive, Cross-Sectional study to determine the frequency of anti-HEV IgG antibodies was evaluated using enzyme-linked immunosorbent assay (ELISA) on 321 pregnant women referred to Alzahra health centers of Tabriz for pursuing pregnancy. Only ten (3.1%) of 321 cases had positive results for anti-HEV IgG. Multivariate analysis of socio-demographic and behavioral characteristics of the pregnant women showed that HEV was associated with availability of potable water at home (p=0.007). The Seroprevalence anti-HEV IgG is low in the pregnant women; maybe it is related to the availability of potable water at home or high level of higen.

Keywords

Pregnancy, Hepatitis E, women