Clinical Trials in the Therapeutic Application of Embryonic and Adult Stem Cells for Cardiovascular Disease

Cardiovascular disease (CVD) is a leading cause of morbidity and mortality worldwide, representing a group of disorders characterized by loss of cardiac function as a result of irreversible damage to cardiomyocytes which results in scar tissue formation. Stem cell therapy are a viable option to improve cardiac function and to promote the repair and regeneration of the myocardium. Several preclinical and clinical trials have shown that transplantation of functional and healthy SCs can promote myocardial regeneration and repair. Here, we focus on the therapeutic applications of embryonic stem cells and adult stem cells to human CVD.