International Journal of Medical Research & Health Sciences
  • Year: 2017
  • Volume: 6
  • Issue: 4

Prevalence of Viral Hepatitis (A, B and C) among Haemophilic Children

  • Author:
  • Mohammed Salah Ali1,, Mohammed Sayed Hemeda2, Ahmed Mohesn Abd El-hakem2, Kamel Soliman Hammad3
  • Total Page Count: 6
  • Page Number: 21 to 26

1Al-Azhar University, Cairo, Egypt

2Department of Paediatrics, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

3Department of Clinical Pathology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

*Corresponding e-mail: Roaarody721@gmail.com

Online published on 15 November, 2018.

Abstract

Haemophilia is a rare haematological disease characterized by prolonged bleeding due to deficiency of coagulating factor 8 and factor 9. This is cross sectional study carried out at paediatric haematology unit Al-Azhar university hospital, Cairo, Egypt, and paediatric haematology unit of El Mabarah-Hospital-Health Insurance Organization, Zagazig, Egypt, during March 2014 to March 2016. One hundred male patients were screened for hepatitis (A, B, and C). Mean age was 11.47 ± 4.4 years old. About 95% with haemophilia A, 4% haemophilia B and 1 patient had combined haemophilia A and family history of hepatitis was 21%. Consanguinity was 28%. Similar condition in the family was 36%. Ecchymosis as clinical manifestation was 64%, haemarthrosis was 62% and jaundice detected in 35% of cases. Severity was mild 20%, moderate 47% and severe was 33%. Most affected joint was knee joint and represented 41%. Blood transfusion, cryoprecipitate were major risk factors for transmitting of hepatitis C positive cases. HAV was 7%, HBV was 0% and hepatitis C was 65%.

HCV is still high in haemophilic and represent a major problem.

Early detection, treatment, and further investigation of hepatitis C virus in haemophilic children.

Keywords

Haemophilia, viral hepatitis