1Department of Liver Transplant Unit, Shaikh Zayed Hospital Medical Complex, Lahore, Pakistan
2Department of General Surgery, Ameer Udin Medical College/PGMI, Lahore General Hospital, Lahore, Pakistan
3Department of Environmental Design, Health and Nutritional Sciences, Allama Iqbal Open University, Islamabad, Pakistan
4Shalamar Institute of Health Sciences, Lahore, Pakistan
5FMH College of Medicine and Dentistry, Lahore, Pakistan
6Akhtar Saeed Medical and Dental College, Lahore, Pakistan
7Department of Public Health and Community Medicine, Shaikh Khalifa Bin Zayed Al-Nahyan Medical College and Shaikh Zayed Postgraduate Medical Institute, Shaikh Zayed Medical Complex, Lahore, Pakistan
*Corresponding e-mail: Sofia.kausar@yahoo.com
Online published on 1 October, 2020.
The aim of the trial was to measure the effect of apple cider vinegar on glycemic control and biochemical parameters in type 2 diabetes mellitus (DM) patients with poor glycemic control.
A single-blind, randomized, placebo-controlled trial was conducted on 110 eligible types 2 DM patients who were selected and allocated into 2 groups. The interventional group was given 15 ml apple cider vinegar in 200 ml water during dinner for 3 months-while the other group was placebo. Before and after HbA1C (glycosylated hemoglobin), fasting lipid profile, fasting-blood sugar, anthropometrics, and dietary changes were assessed and analyzed using IBM SPSS version 20, through statistical tests. Formal ethical approval was obtained from the local institutional review board.
Significant mean change was found in interventional group in HbA1c (p<0.001), blood sugar fasting (p<0.001), total cholesterol (p=0.002), triglyceride (p=0.002) and hip-waist ratio (p=0.002). No significant change was observed in the mean of these statistics in the placebo group. No significant change was observed in height, weight, mid-upper arm-ratio, and low density lipoprotein, high density lipoprotein and food frequency in intervention and placebo groups before and after.
Apple cider vinegar if used regularly is effective in controlling diabetes, lowering hypercholesterolemia and hypertriglyceridemia in DM type 2 patients.
Vinegar, Diabetes, Hyperglycemia, Hypercholesterolemia, Nutraceutical
