International Journal of Medical Research & Health Sciences
  • Year: 2019
  • Volume: 8
  • Issue: 5

Case report on methylene blue induced hemolytic anemia

  • Author:
  • T.S Sulfath1, M Bhanu Kumar2, Koneru Vasavi1, Aparna R Menon1, Ann V Kuruvilla1,
  • Total Page Count: 3
  • Page Number: 83 to 85

1Department of Pharmacy Practice, JSS College of Pharmacy, Mysuru, Jagadguru Shri Shivarathreeshwara Academy of Higher Education and Research, Karnataka, India

2Department of General Medicine, JSS Medical College and Hospital, JSS Academy of Higher Education and Research, Karnataka, India

*Corresponding e-mail: anniekuruvilla@jssuni.edu.in

Online published on 1 October, 2020.

Abstract

A 22-years old male patient was admitted to a tertiary care hospital with complaints of an alleged history of intentional poisoning (organophosphorus compound and nitrofurantoin) and developed hemolytic anemia after receiving-methylene blue for 8 days. The patient presented with hematuria and hemoglobin level 3.1 which confirmed hemolytic-anemia G6PD level was normal. Methylene blue was discontinued and PRBC transfusion (3 pints) was given. After 4 days of blood transfusion, the patient’s Hb level became 9.4 g/dl. Causality assessment was suggestive of a probable relationship between the drug and reaction.

Keywords

Hemolytic anemia, Methylene blue, G6PD