Antiasthmatic active compound from the roots of acorus calamus (Linn.)

The isolation of Antiasthmatic compound (Luteolin-8-C-β-D-Glucopyranoside) from ethyl acetate extract of the roots of Acorus Calamus (linn.) are characterized by different spectroscopic methods IR, ¹H NMR, ¹³C NMR and FABMAS. The ethanolic extracts of the plants produced a dose dependent increase in respiratory capacity in the histamine-induced bronchospasm in guinea pigs. The compound showed the results at 8.42%, 5.59 % and16.39 % at doses 50,100, 200 mg/kg in which the significant protection was found at 16.39 % which was found to be more close to the reference compound salbutamol which was 63.25 %.