Indian Journal of Nuclear Medicine
  • Year: 2004
  • Volume: 19
  • Issue: 3

Myocardial Apoptosis for the Nuclear Physician

  • Author:
  • Gurusher S. Panjrath, Diwakar Jain*
  • Total Page Count: 7
  • Page Number: 68 to 74

Division of Cardiology, Drexel University College of Medicine, Philadelphia, PA, USA

*Correspondence to: Diwakar Jain, MD, Professor of Medicine, Director of Nuclear Cardiology, 245 N.15 th Street, MS 470, Philadelphia, PA 19102-1192, Telephone: 215-762-4990 Fax: 215-762-1525, E-mail: diwakar.jain@drexel.edu

Abstract

Nuclear imaging provides a unique opportunity to image various biological processes, receptor functions and molecular interactions in various organ systems in intact animals and humans under various physiological conditions. These techniques have enhanced our understanding of pathophysiology of various disease processes.

In the last few years, myocardial apoptosis has attracted a lot of interest by the clinician, biomedical researcher and imaging scientist, because of its potential for enhancing our understanding of congestive heart failure (CHF) and its role in acute ischemia/reperfusion injury, plaque rupture and acute coronary events and thus development of strategies for their prevention and possible reversal.

Keywords

apoptosis, nuclear imaging, annexin V