12nd year resident, Dept. of Obstetrics & Gynecology, C U Shah Medical College, Surendranagar
2Associate professor, Dept. of Obstetrics & Gynecology, C U Shah Medical College, Surendranagar
3Professor and Head of Department, Dept. of Obstetrics & Gynecology, C U Shah Medical College, Surendranagar
*Corresponding Author: Email: Mehul.sangani@yahoo.in
Online published on 18 December, 2015.
Hemolytic Uremic Syndrome is characterized by microangiopathic hemolytic anaemia, thrombocytopenia, renal failure, fever and altered sensorium. A 28 years old primigravida patient was admitted on 18-6-2014 with history of 9 MOA and AML of 1 yr with lower abdominal pain since 10–12 hrs & leaking per vaginum. On per abdominal examination, uterus was full term, cephalic with longitudinal lie. Pt was operated for LSCS for oligohydraminos with all normal investigations. Postoperatively, patient had decreased urine output. HUS was suspected on basis of unexplained thrombocytopenia with normal other coagulation profile, presence of fragmented RBCs, increased serum LDH, unexplained altered renal function, fever in absence of any foci of infection and altered sensorium. Patient was treated with Plasmapheresis, hemodialysis, noninvasive ventilation, other supportive medical treatment and Inj. FFP 8 units, Inj. PCV 3 units.
Hemolytic Uremic Syndrome, ADAMTS-13 (A disintegrin and metalloprotease with a thrombospondin type 1 motif, member 13), Plasmapheresis, serum LDH, Hemodialysis
