Indian Journal of Obstetrics and Gynecology Research
  • Year: 2015
  • Volume: 2
  • Issue: 4

Serum Lipid Profile In Pregnancies Complicated By Pre-Eclampsia

1Assistant Professor, Department of Obstetrics and Gynaecology, Gandhi Medical College, Secunderabad, Telengana State

2Assistant Professor, Department of Obstetrics and Gynaecology, Gandhi Medical College, Secunderabad, Telengana State

3Post Graduate, Department of Obstetrics and Gynaecology, Gandhi Medical College, Secunderabad, Telengana State

4Professor & Head, Department of Obstetrics and Gynaecology, Gandhi Medical College, Secunderabad, Telengana State

*Corresponding Author: E-mail: vijayakrishna766@gmail.com

Online published on 4 February, 2016.

Abstract

To compare the changes in lipid profile in women with pre-eclampsia to normotensive pregnant women.

This prospective observational study conducted in 300 patients, 150 being normotensive pregnant women and 150 hypertensive pregnant women. Lipid profile was estimated and compared.

There is a significant increase in triglycerides, total cholesterol, LDL & VLDL in the cases group but no significant difference in HDL between both groups.

Pregnancy is associated with physiological hyperlipidemia. But abnormal increase in triglycerides, total cholesterol, LDL & VLDL could contribute to promotion of oxidative stress and vascular injury leading to pre-eclampsia.

Keywords

Pre-eclampsia, CHL-Total cholesterol (mg/dl), TGL-Triglycerides (mg/dl), LDL-Low density lipoprotein (mg/dl), HDL-High density lipoprotein (mg/dl), VLDL-Very low density lipoprotein (mg/dl), BMI-Body mass Index (kg/m2)