Comparative evaluation of Chlosite^CE gel and hexigel^R application in management of persistent periodontal pockets: -a randomized, controlled clinical trial

OBJECTIVE-In this randomized controlled clinical trial(RCT) we have compared clinical and microbiological effect of two different concentrations of commercially available chlorhexidine gel (CHLOSITE^CE and HEXIGEL^R) in treatment of localized periodontal pocket as an adjunct to scaling & root planing (SRP).

MATERIALS AND METHODS-30 patients were selected and divided into 3 groups. Patients of group A were treated by SRP, group B by SRP + HEXIGEL (1% Chlorhexidine) application and group C were assigned to CHLOSITE (1.5% Chlorhexidine). After gel application treated sites were sealed by Coe-pack. Clinical (Clinical attachment level) and microbiological parameters (colony forming units per ml of GCF) were recorded at baseline and after 3 months. Statistical analysis of the data was calculated using paired and unpaired t test.

RESULTS-Clinical improvement was seen in all groups with mean clinical attachment level gain of 12.84%, 21.44% and 34.95% for groups A, B and C respectively. The mean microbial count reduction for group A, B and C were 27.3%, 37.47% and 57.8% respectively.

CONCLUSION-This RCT showed that placement of CHLOSITE^CE gel as an adjunct to SRP for treatment of localized periodontal pockets had better clinical and microbiological results as compared to other local drug delivery systems used till date.