Serum Total Estradiol Level is Associated with Waist Circumference in Adult Males

Obesity is becoming pandemic and in developing country like India problem of obesity is also growing at a very fast rate. In men Estradiol (E2) is important must be kept in balance for good health. Serum estradiol changes with Body weight. This study was conducted to see the association of serum total estradiol (E2) level with the waist circumference in adult males. It was a cross sectional study, conducted on 89 adult males (aged 18–50 years). Anthropometric measurement i.e. waist circumference (cm) was taken as a criteria for classifying normal weight and overweight & obese males. The morning venous blood sample was drawn between 8–11 A.M. from each subject and serum was separated. Serum Total estradiol was measured using ELISA. When compared with waist circumference, serum total estradiol in normal weight "Group A" with W.C. < 90cm, was 19.61±8.56pg/ml and in overweight and obese subjects, "Group B" with W.C. ≥ 90cm it was 52.10±29.83 pg/ml. Thus it was concluded that Serum Total Estradiol level significantly increased in "Group B" (W.C. ≥ 90cm) as compared to subjects with" Group A" (W.C.< 90cm).Therefore we can delineate that serum total estradiol might increase significantly because of increased abdominal fat mass in overweight and obese subjects i.e. subjects who had increased waist circumference(≥ 90 cm)