1Asst. Professor, Department of Physiology, SRDC, Faridabad (HR)
2HOD, Department of Physiology, HIMS, Jolly Grant, Dehradun
3Associate Professor, Physiology, HIMS, Jolly Grant, Dehradun
4Professor, Department of Surgery, Oncology Unit, HIMS, Jolly Grant, Dehradun
*Corresponding author: Manveen Kaur, Asst. Professor, Department Of Physiology, Sudha Rustagi College of Dental Sciences & Research, Kheri More, Sector - 89, Faridabad (HR) E - mail: drmanveenk@gmail.com, Ph. No.: 09910022612
Online published on 4 April, 2014.
Muscle hypothesis implicates abnormalities in peripheral muscle as a source of stimulus for symptoms and reflex abnormalities seen in chronic heart failure.
To evaluate ergoreflex contribution to CRRto isometric exercise in CP.
We studied 30 CP (age- 56.1±0.7) and 30 age matched normal subjects (age 55.0±0.7). Post exercise regional circulatory occlusion method (PE-RCO) was used to assess ergoreflex. We compared cardiaorespiratory responses to sustained handgrip and during a 3-minute period of post exercise regional circulatory occlusion (PE-RCO). Contributions made specifically by ergoreflex to cardiorespiratory parameters in responses to exercise were derived by calculating absolute difference in these parameters during 10min recovery between with PE-RCO and without PE-RCO. CP showed significant ergoreflex activation compared with control subjects in term of Heart Rate and Respiratory Rate.
Ergoreflex is overactive in CP.
Cancer, Cachexia, Ergoreceptors, Ergoreflex, CCRCardiorespiratory Responses, CPCancer Patients
