International Journal of Physiology
  • Year: 2014
  • Volume: 2
  • Issue: 2

A Study of Lipid Profile Level in Type 2 Diabetes Mellitus Patients in the Age Group of 35 -70 Years

1Assistant Professor, Department of Physiology, Saraswathi Institute of Medical Sciences, Anwarpur, Hapur, Uttar Pradesh, India

2Assistant Professor, Department of Medicine, Saraswathi Institute of Medical Sciences, Anwarpur, Hapur, Uttar Pradesh, India

3Assistant Professor, Department of Surgery, Saraswathi Institute of Medical Sciences, Anwarpur, Hapur, Uttar Pradesh, India

4Assistant Professor, Department of Medicine, Saraswathi Institute of Medical Sciences, Anwarpur, Hapur, Uttar Pradesh, India

*Corresponding author: Narendra Kumar, Flat No. 10, Staff Quarters, S.I.M.S. Campus, Anwarpur District. Hapur, U.P., Email.. drnarendra.kumar2@gmail.com, Mob: 09536360442, 09412802011

Online published on 24 September, 2014.

Abstract

Patients with diabetes have a 2- to 3-fold higher rate of coronary artery disease (CAD), a 4-fold higher risk of dying during acute myocardial infarction (MI), and 2-fold higher risk of post-MI morbidity than non diabetic persons. Diabetic atherosclerosis, reminded us that this is a heterogeneous condition, and that dyslipidemia is only 1 aspect of the patho physiology. However, dyslipidemia is the most readily measured and, at the present time, the most readily treated aspect of the problem.

In this study 200 patient enrolled, 100 were diabetic and 100 were normally control with age group 35 year to 70yr and result shows There was statistically significant rise in serum total cholesterol (218.11 ± 9.556) in diabetics as compared to Control subjects (194.74 ± 8.105), (t value = 18.651) and (P value = 0.001). There was statistically significant rise in Serum total glycerides (120.56 ± 12.285) in diabetics as compared to Control subjects (106.92 ± 11.686), (t value = 8.045) and (P value = 0.0001). There was statistically significant rise in Fasting Blood Sugar (120.86 ± 9.000) in diabetics as compared to Control subjects (87.97 ± 6.731), (t value = 29.265) and (P value = 0.0001).There was statistically significant rise in LDL (165.41 ± 22.684) in diabetics as compared to Control subjects (101.97 ± 22.917), (t value = 19.674) and (P value = 0.001). There was statistically significant decrease in HDL (43.19 ± 3.421) in diabetics as compared to Control subjects (46.39 ± 3.583), (t value = 6.460) and (P value = 0.0001).

Keywords

Dyslipidemia, coronary artery disease (CAD), HDL cholesterol, LDL-cholesterol