Department of Physiology, S.N Medical College, Agra, Uttar Pradesh, India
To study the effects of Magnesium supplementation on motor nerve conduction velocity of common peroneal nerve in patients of diabetic neuropathy.
The study was done in 60 diabetic neuropathy patients attending the neurology O.P.D of S.N Medical college & hospital between February 2009 to August 2010. These patients were divided into two groups. Gp I (n=30) receiving Magnesium and Metformin therapy for a period of 16 weeks. Gp II (n=30) receiving only Metformin therapy.
The blood samples were collected and analysed for S.Magnesium and fasting blood glucose at 0, 4, 8, 16 weeks respectively. Nerve conduction velocity for common peroneal nerve was done at 0, 4, 8, 16 weeks respectively.
Average of males in group 1 was 54.36±1.18yrs and of females was 53.09±1.47 yrs and in groupII was 55.94±1.62 yrs and of females was 52.83±1.58 yrs respectively.
Mean baseline value for N.C.V of Common Peroneal Nerve in group I was 38.08±0.68 and after treatment values at 4 weeks was 39.31±0.61, at 8 weeks 40.58±0.62, at 16 weeks was 44.19±0.77 respectively (P<0.05). Mean baseline value for N.C.V of common peroneal nerve in group II was 37.84±0.75 and after treatment values at 4 weeks was 37.24±0.76, at 8 weeks 38.40±0.76, at 16 weeks was 39.64±0.80 respectively (P>0.05). Stastically significant difference was observed in groupI patients for nerve conduction velocity before and after treatment values at 16 weeks(p<0.05). Stastically insignificant difference was observed in group II patients for nerve conduction velocity before and after treatment values at 16 weeks(p>0.05).
Diabetic neuropathy, Magnesium Supplementation, Motor Nerve Conduction Velocity (Common Peroneal Nerve)
