1Associate Professor, Department of Physiology, SRM Medical College, Hospital and Research Centre, Potheri
2Assistant Professor, Department of Physiology, M.S. Ramaiah Medical College, Bangalore
3Associate Professor, Department of Physiology, SRM Medical College, Hospital and Research Centre, Potheri
4Professor, Department of Physiology, M.S. Ramaiah Medical College, Bangalore
5Professor, Department of Physiology, SRM Medical College, Hospital and Research Centre, Potheri
Online published on 11 February, 2016.
Microalbuminuria is the presence of albumin in urine above the normal level but below the detectable range of conventional methods. Its presence is an early marker of diabetic nephropathy.
Detect prevalence of microalbuminuria in type 2 diabetic patients.
Correlate microalbuminuria with age, sex and duration of disease.
Correlate microalbuminuria with blood sugar (fasting and post-prandial), serum creatinine and Blood urea nitrogen (BUN).
Compare microalbuminuria in controlled (HbA1c<7) and uncontrolled (HbA1c> 7) type II diabetics.
Around 100 cases of diabetic patients of age group 30–80 years, with duration of diabetics more than one year were examined for fasting and postprandial blood sugar(FBS and PPBS), HbA1c, BUN and serum creatinine. Also 24 hour urine sample was analysed for microalbuminuria by turbidometric method.
The prevalence of microalbuminuria was 48% with p value 0.004. Also a significant correlation of microalbuminuria was seen with FBS, PPBS, BUN, and serum creatinine. However no correlation of microalbuminuria was established with HbA1c and duration of disease. Further microalbuminuria was increased in uncontrolled diabetics than controlled diabetics though it is not statistically significant.
Our study concludes that microalbuminuria is essential for early detection of diabetic nephropathy. Therefore it is recommended that microalbuminuria test should be done at regular intervals for type II diabetes mellitus.
Type II diabetics, microalbuminuria, HbA1c, diabetic nephropathy
