1Associate Professor, Department of Physiology, Osmania Medical College, Hyderabad, Telangana
2Assistant Professor, Department of Physiology, Kamineni Institute of Medical Sciences, NKP
Diabetes mellitus is a metabolic disorder, which has become a major health challenge worldwide. Diabetic neuropathy is most commonly occurring microvascular complication. It has a long asymptomatic stage which is accelerated by poor glycemic control. Nerve conduction study has become an important non-invasive tool for screening of nerve lesion in subclinical stages.
To assess median nerve velocity and its association with duration of diabetes, body mass index and glycemic control.
Present study was conducted in Osmania Medical College Hospital, Hyderabad. Fifty type II diabetes mellitus patients with history of diabetes for 1–10 years. They were compared with 50 age & gender matched healthy individuals. Blood sugar & glycated heamoglobin (HbA1c) was estimated followed by nerve conduction study.
Data was analysed statistically using unpaired students t-test and Chi square test. ‘p’ value less than 0.05 was considered significant. Nerve conduction velocity progressively decreased in diabetic group. There is negative correlation between sensory nerve conduction velocity & glycemic control.
Present study suggests that there is progressive slowing of sensory nerves in diabetics which is accelerated by poor glycemic control. With proper glycemic control the motor nerve changes and complications of sensory disturbances can be prevented.
Diabetes Mellitus, Glycated hemoglobin (HbA1c), Neuropathy, Nerve conduction velocity
