International Journal of Physiology
  • Year: 2017
  • Volume: 5
  • Issue: 1

A Comparative Study of Serum Total Antioxidant Capacity (TAC) in Male Smokers and Non Smokers

1Associate Professor, Department of Physiology, Nimra Institute of Medical Sciences, Vijayawada, Andhra Pradesh, India

2Assistant Professor, Department of Pediatrics, Katuri Medical College, Guntur, Andhra Pradesh, India

*Address for Correspondence: Dr. Jayaram Gadham Associate Professor, Department of Physiology, Nimra Institute of Medical Sciences, Vijayawada, Andhra Pradesh, India, Pin code: 521456, Email: drjayram@yahoo.com

Online published on 13 February, 2017.

Abstract

Smoking is characterized by increased free radicals and stress oxidative.

To compare total antioxidant capacity between adult male smokers and non smokers.

A total of 110 male subjects were involved in this study. 56 of them were non smokers and another 54 of them were smokers. Age of the smokers and non smokers were ranged between 30 to 45 years. Venous blood was collected from subjects after an overnight fast in the morning. Blood samples were used for evaluation serum total antioxidant capacity. TAC was measured by using the total ferric reducing assay.

Data showed that total antioxidant capacity was significantly higher in smoker than non-smoker subject (p <0.05). Based on the Pearson correlation coefficient, there was no a significant correlation between the number of smoked cigarettes and the TAC (r =-0.127, p = 0.723)

This study concluded that smoking is associated with decreased antioxidant capacity and stress oxidative.

Keywords

Free radicals, Antioxidant capacity, Smoking