International Journal of Physiology
  • Year: 2017
  • Volume: 5
  • Issue: 1

Comparison of Arterial Stiffness in Healthy Volunteers and Chronic Smokers Using Pulse Wave Velocity

1M.B.B.S, Department of Physiology, Narayana Medical College, Nellore

2Assistant Professor, Department of Physiology, Narayana Medical College, Nellore

3Professor, Department of Physiology, Narayana Medical College, Nellore

*Address for Correspondence: Dr. J Bhaavya Anusha M.B.B.S, Narayana Medical College, Nellore, Mobile: 8500205256, E-mail id: bhaavya2014@gmail.com

Online published on 13 February, 2017.

Abstract

Arterial stiffness is a growing epidemic associated with increased risk of cardiovascular events, dementia, and death. Decreased compliance of the central vasculature alters arterial pressure and flow dynamics and impacts cardiac performance and coronary perfusion. These complications are responsible for negative effect on quality of life with smoking. Hence it has become important that chronic complications are recognized early and necessary interventions are made.

24 smokers aged between 20-40yrs, with duration of smoking more than 3yrs and 24 non smokers aged between 20-40yrs were selected and subjected for Lead II ECG recording and finger pulse photoplethysmography.

1. To determine arterial stiffness in healthy volunteers by recording pulse wave velocity.

2. To compare pulse wave velocity in healthy volunteers and chronic smokers.

There was a positive correlation between duration of smoking and PWV with r value 0.26. An increase in the systolic and diastolic blood pressure was observed with out significance. The resting heart rate was also markedly increased. The mean PWV in control group and test group was 4.2 mts/sec and 5.48 mts/sec respectively.

Arterial stiffness in simple term describes the rigidity of arterial wall. Arterial stiffness can be analyzed by recording pulse wave velocity. Therefore complete understanding the effects of smoking on vascular endothelium can prevent deleterious complications.

Keywords

Pulse Wave Velocity (PWV), Arterial stiffness, Chronic smoking, Radial artery, Pulse Transit Time (PTT)