International Journal of Physiology
  • Year: 2017
  • Volume: 5
  • Issue: 1

A Case Control Study of Levels of Serum Magnesium and HbA1c among Patients with Type 2 Diabetes

1Associate Professor, Department of Physiology, Apollo Institute of Medical Sciences and Research, Chittoor, Andhra Pradesh, India

2Assistant Professor, Department of Physiology, Apollo Institute of Medical Sciences and Research, Chittoor, Andhra Pradesh, India

*Address for Correspondence: Dr. Srinivasa Jayachandra Associate Professor, Department of Physiology, Apollo Institute Of Medical Sciences & Research Murukambattu, Chittoor-517127, Andhra Pradesh, India-Email: jayachandra.srinivasa@gmail.com

Online published on 13 February, 2017.

Abstract

Magnesium (Mg) deficiency is a common problem in diabetic patients. Deficiency of Mg may increase the incidence of diabetes mellitus (DM) and occurrence of diabetic complications.

To assess the serum magnesium and HbA1c levels in type 2 diabetes patients.

This is a case control study and the sample size was 60 (30 type 2 diabetic patients and 30 controls). Serum magnesium levels and HbA1c were measured. Statistical analysis was performed using SPSS 16.0 (SPSS Inc., Chicago, IL, USA)

The serum magnesium levels are significantly lower in diabetic patients when compared to controls (P<0.001). There was a significant correlation between the diabetic status and low serum magnesium levels. The values of HbA1C (%) were positively correlated with blood glucose level and negatively correlated with serum magnesium levels.

Hypomagnesaemia is associated with micro vascular complications and poor glycemic control. It is important to regularly monitor magnesium levels in all type 2 diabetic patients.

Keywords

Type 2 Diabetes mellitus, Insulin resistance, Magnesium