International Journal of Physiology

  • Year: 2017
  • Volume: 5
  • Issue: 2

A Comparative Study of QT Interval and Its Dispersion among Hypertensive and Normotensive Subjects

1Assistant Professor, Department of Physiology, MES Medical College, Perinthalmanna, Kerala

2Associate Professor, Department of Anatomy, MES Medical College, Perinthalmanna, Kerala

Abstract

Hypertension is the most prevalent non communicable disease and it markedly increases both morbidity and mortality. Variation in QT intervals has been proposed as early markers of vulnerability to ventricular arrhythmias and considered as potential predictors of mortality. This study was taken up to assess early detection of changes in QT interval among hypertensive subjects and early management of cardiac abnormalities.

To assess the cardiac function status in patients with essential hypertension by analyzing QT interval, corrected QT intervals (QTc) and QT dispersion (QTd).

50 hypertensive and 50 normotensive male subjects between the age group of 40–60 years were selected. Computerized ECG system with Nivi qure software was used for the study. Mean QT intervals, QTc and their dispersions (QTd), were assessed to observe cardiac function status. Statistical analysis was done by using paired “t” test.

Mean QT intervals, QTc intervals and their dispersions were significantly higher in hypertensive subjects (p < 0.001).

The levels of both systolic and diastolic blood pressures are related to the generation of ventricular rhythm problems either via increasing left ventricular mass which results in an increase in QT parameter measurements.

Keywords

Cardiac arrhythmias, Hypertension, QT intervals