A Study of Nerve Conduction Velocity in Newly Diagnosed Hyperthyroid Females

Hyperthyroidism is a common endocrinological disorder due to excessive levels of T4 and T3 affecting primarily muscle function and the central nervous system. It is associated with neuropsychiatric and neurologic syndromes and myopathy. To evaluate neuromuscular dysfunction in newly diagnosed hyperthyroid patients, nerve conduction studies were done. A significant reduction in peroneal nerve motor amplitude was observed with P value of 0.05. In sural nerve sensory conduction study, the latency and conduction velocity showed significant difference from control group. The H reflex study was also done but it did not show any difference from control group. In contrast to the previous studies we found in our study that sensory motor axonalneuropathy also occurs in hyperthyroid patients. As a conclusion electrophysiological studies can be useful in the diagnosis of asymptomatic polyneuropathy in hyperthyroid patients.