1Assistant Professor, Department of Physiology, Shridevi Institute of Medical Sciences and Research Hospital, Tumkur
2Assistant professor, Department of Physiology, Travancore Medical College and Hospital, Kollam
3Professor and Head of the Department, Department of Physiology, Bangalore Medical College and Research Institute, Bangalore
*Corresponding author: Dr. K Pushpa, Assistant Professor, Department of Physiology, Shridevi Institute of Medical Sciences and Research Hospital, Sira road, Tumkur, Karnataka-572106, Email id-dr.pushpahalesh@gmail.com
Online published on 18 July, 2017.
Coronary heart disease is becoming a major cause of mortality in India and the purpose of the study was to identify the risk factors already present in the offspring of CHD patients.
To study and compare the Waist hip ratio and lipid profile in offspring of coronary heart disease patients and controls.
Study was conducted between 50 subjects (18–30 yrs) with parental history of CHD and age and sex matched 50 controls (without the parental history of CHD). Serum lipid profile which included Total cholesterol, LDL, HDL, VLDL, TG levels and TC: HDL ratio was estimated and Waist hip ratio measured. The results were tabulated and statistically analyzed.
Control group had excellent Waist hip ratio (M<0.85, F<0.75) (p=0.05), as compared to study group. Serum TC (p=0.004) and LDL (p=0.006) levels were significantly higher in study group and TC: HDL ratio or risk ratio (p=0.023) was low in control group.
Offspring of CHD patients should be advised to maintain their lipid levels in optimal range and inculcate changes in their lifestyle so as to prevent CHD in future. Intake of junk foods and saturated fat to be avoided and physical activity has to be increased to reduce the risk of CHD.
coronary heart disease, family history, lipid profile, risk ratio, waist to hip ratio
