1Tutor, Department of Physiology, Indira Gandhi Institute of Medical Sciences, Patna
2Professor & HOD, Physiology, Indira Gandhi Institute of Medical Sciences, Patna
*Corresponding author: Dr. Swati Sinha, Tutor, Physiology, IGIMS, Patna-14, Bihar, Dr.swatisinha123@gmail.com, Mob.: 9661548621
Online published on 18 July, 2017.
Diabetes mellitus (DM) is a leading health care problem with long term complications. Studies have shown compromised lung function in type-2 DM but there is still lack of clarity on its relation with disease duration. This study was carried out to determine effect of duration of type-2 DM on pulmonary function.
We aimed to investigate if any relation exists between deterioration of lung function and duration of disease.
A cross sectional study was carried out on 80 diagnosed type-2 DM patients from the rural population of Sullia who attended KVG medical college OPD, they were non smokers and did not suffer from any cardiopulmonary disease. They were divided in two groups based on disease duration, Group-A had 38 subjects with diabetes for 2-4years and Group-B consisted of 42 subjects with 8-10years of disease. PFT was performed using a digital spirometer (UNI-EM Spiromin). Statistical analysis was done using unpaired t test.
FVC (in L) in Group-A and B was 4±0.67 and 3.06±0.39 respectively with p<0.0001. FEV1 (in L) in Group-A and B was 3.6±0.63 and 2.86±0.34 respectively with p<0.0001. FEV1/FVC ratio (in %) in Group-A and B was 90.26±5.08 and 93.74±4.2 respectively with p=0.03. So, FVC and FEV1 showed extremely significant decrease, FEV1/FVC ratio showed significant increase and PEFR on the other hand showed no significant change with increase in duration of diabetes.
PFT findings in this study indicate that, as duration of type-2 DM increases, restrictive lung disease becomes more prominent.
lung function, type 2 diabetes mellitus, spirometr
