International Journal of Physiology
  • Year: 2017
  • Volume: 5
  • Issue: 2

Thyroid Hormone Levels in Patients with Polycystic Ovarian Syndrome

1Assistant Professor, Department of Physiology, Kamineni Institute of Medical Sciences, Nalgonda

2Associate Professor, Department of Physiology, Kamineni Institute of Medical Sciences, Nalgonda

3Gynaecologist, Government Hospital, Bagalkot

Online published on 18 July, 2017.

Abstract

Polycystic ovarian syndrome, commonly known as PCOS, is an endocrine disorder seen in women of reproductive age. Polycystic ovarian syndrome is estimated to effect 4–12% of women throughout the world and is most commonly characterized by hyperandrogenism and insulin resistance each of which affect 60% to 80% of PCOS patients and 50–80% of PCOS women respectively.

To evaluate the levels of thyroid hormones in women with PCOS.

80 female patients with PCOS based on Rotterdam criteria, 80 volunteer females included as controls, serum levels of TSH, T3 and T4 were tested in two groups.

Significant increase in TSH along with a significant decrease in T3 and T4 in PCOS females matched against controls (p< 0.05).

PCOS is linked to hypothyroidism and more studies should be carried to reveal the precise relationship.

Keywords

Thyroid hormones, polycystic ovarian syndrome, T3, T4, TSH