1Assistant Professor, Department of Physiology, Travancore Medical College and Hospital, Kollam
2Assistant Professor, Department of Physiology, Shridevi Institute of Medical sciences and Research Hospital, Tumakuru
*Corresponding Author: Dr. Pushpa K Assistant Professor Department of Physiology, Shridevi Institute of Medical sciences and Research Hospital, Sira road, Tumakuru, Karnataka-572106 Email id: dr.pushpahalesh@gmail.com
Online published on 10 April, 2018.
smoking is an increasing health problem in developing countries like India. Cigarette smoking is an important risk factor for peripheral, coronary and cerebral atherosclerosis. Hence an attempt is made in this study to know possible effect of cigratte smoking on lipid profile.
To compare the lipid profiles between chronic smokers and non smokers and to relate lipid profile with smoking pack years.
25 active male smokers considering exclusion criteria in age group of 30-55yrs and age, BMI matched male healthy control subjects (25) were assessed for clinical details, dietary habits and smoking.standard methods were adopted to check the lipid levels. Total cholestrol/HDL ratio is also calculated. The data was analyzed statistically.
The total cholestrol (213.96±40.81, p<0.001), VLDL (45.44±19.43, p=0.017), LDL(126.12±39.81, p=0.001), Triglycerides (242.88±95.04, p=0.016) and total cholestrol/HDL ratio (6.96±1.78, p<0.001) were found to be signifcantly higher in smokers when compared to non smokers. Total cholestrol(244.91±37.58, p<0.001) and LDL(142.55±46.79, p=0.066) were significantly higher among smokers with >10 pack years compared to smokers with ≤10 pack years.
There was significantly abnormal lipid profile in smokers when compared to non smokers. The total cholesterol/HDL ratio can be used to predict ischemic heart disorders. Number of pack years was directly proportional to abnormal lipid profile.
Smoking, serum lipid profiles, chronic smokers, coronary and cerebral atherosclerosis, Ischemic heart disorders
