International Journal of Physiology

Anesthesia is the ultimate trust of the patient reposed in the doctor In anesthesia, we are targeting the nervous system. But, throughout the surgical procedure, we are monitoring the cardiovascular and respiratory status. An effort has been made in this study to monitor the targeted system and to show that it is better and more advantageous when integrated with the cardiovascular monitoring. The aim was to show the variation in cerebral entropy in different phases of anesthesia and to study the benefits in using it as a monitor for the depth of anesthesia. After ethics committee approval, 40 patients in the age group of 15 to 65 belonging to ASA grade I and II scheduled for elective surgery under general anesthesia were enrolled for this study. Baseline Response Entropy (RE), State Entropy (SE), Heart Rate(HR), Blood Pressure (BP) values were recorded before the induction of anesthetic drugs. Entropy values were recorded with the instrument Date × Ohmeda E-entropy module. Anesthetic drugs used were same for all the patients. The RE and SE recordings were recorded in all the five phases: Induction, Intubation, Post Intubation, Maintenance and Recovery at specific time intervals. Statistical analysis was done with ONE WAY ANOVA. The results showed that the mean RE and mean SE values are significantly varying in all the phases when compared to the baseline values (p value <.001) as evidenced by tukeys and tamhanes tests. The RE and SE changes are found to be varying more significantly than MABP.