International Journal of Physiology
  • Year: 2018
  • Volume: 6
  • Issue: 3

Comparative Study of the P100 Values with Varying Duration of Type 2 Diabetes Mellitus

1Associate Professor, Department of Physiology, GSL Medical College and Hospital, Lakshmipuram, Rajahmundry

2Assistant Professor, Department of Physiology, GSL Medical College and Hospital, Lakshmipuram, Rajahmundry

*Corresponding author: Mohammed Jaffer, Assistant Professor, Department of Physiology, Gsl Medical College and Hospital, Lakshmipuram, Rajahmundry. Mobile No-8867517362, Email Id: mdjafferkp@gmail.com

Online published on 16 July, 2018.

Abstract

The Pattern Reversal Visual Evoked Potentials (PRVEPs) are used in evaluating the normal functioning of the visual pathway. Retinopathy being one of the complications of diabetes effecting the visual pathway, the aim of the study is to compare the P100 values with varying duration of Type 2 Diabetes Mellitus (Type 2 DM).

A cross sectional study was done after obtaining written consent from all subjects and obtaining approval from the Institutional Ethics Committee. PRVEPs were performed using Viking Select neuro-diagnostic system.[Viasys Healthcare, USA].

Three study groups were selected basing on the duration of type 2 DM.

Group 1-30subjects with duration of <5 years.

Group 2-30subjects with duration of 5–10 years

Group 3–30 subjects with duration >10 yrs

Data was analyzed and processed using EPI INFO statistical software using unpaired student t-test (two-tailed). The level of significance was taken as p<0.05.

The intergroup comparative analysis showed that p100 delay was statistically significant. Conclusion-we conclude that p100 latencies increased with the increasing duration of type 2 Diabetes.

Keywords

Retinopathy, PRVEPs, Type 2 Diabetes, duration of Type 2 Diabetes