International Journal of Physiology
  • Year: 2018
  • Volume: 6
  • Issue: 3

Autonomic Nervous System Activity in Migraine Patients

1Assistant Professor, Department of Physiology, KIMS, Hubli

2Tutor, Department of Physiology, BIMS, Belagavi

*Author for Correspondence: Dr. Tahaseen Banu Shaikh, Tutor (MD Physiology), Department of Physiology, Belagavi Institute of Medical Sciences, Belagavi-590001. E-mail: tahaseenbanushaikh@gmail.com

Online published on 16 July, 2018.

Abstract

Headache is among the most common reasons patients seek medical attention. In literature autonomic nervous system (ANS) impairment in migraine is well documented i.e. migraine is of neural origin. Different symptoms of migraine attacks such as nausea, vomiting, diarrhea, pallor, flushing, piloerection and diaphoresis are explained with the instabilities of ANS. Enhanced understanding of the ANS dysfunction in migraine may help to more effectively diagnose, prevent &/or treat migraine.

Thirty migraine female patients aged 25 to 55 were included. Thirty age and gender matched controls were chosen for comparison. Two non-invasive parasympathetic tests and two non-invasive sympathetic tests were performed. Statistical analysis was done by unpaired student‘t’ test.

Parasympathetic tests showed significantly decreased heart rate variation during deep breathing and immediate standing in migraineurs when compared to controls (P<0.05). Sympathetic tests did not show significant difference.

Parasympathetic hypofunction was suggested in our study.

Keywords

Migraine, autonomic function tests