1Assistant Professor, Department of Physiology, Kamineni Institutes of Medical Sciences, Narketpally
2Assistant Professor, Department of Obstetrics and Gynaecology, Kamineni Institutes of Medical Sciences, Narketpally
3Associate Professor, Department of Obstetrics and Gynaecology, Kamineni Institutes of Medical Sciences, Narketpally
4Lecturer, Department of Physiology, Kamineni Institutes of Medical Sciences, Narketpally
5Professor, Department of Paediatrics, Kamineni Institutes of Medical Sciences, Narketpally
Online published on 4 April, 2019.
Infants of diabetic mothers (IDM) are prone to a number of immediate neonatal complications when compared to the babies born to normal mothers. Diabetes mellitus is a risk for the health of both pregnant women and her infant. Its unfavorable effects start in utero and continue after birth. It is known that gestational diabetes mellitus (GDM) increases oxidative stress and decreases antioxidant enzyme activities. Maternal glycemic control has been one of the parameters that determines the occurrence of these problems. In present study we aimed to investigate cord blood mean platelet volume (MPV) of infants of diabetic mothers (IDM).
Forty pregnant women with GDM between 37 to 40 gestational weeks were enrolled as study group together with 40 healthy pregnant women as a control group. The two groups were compared in terms of demographics parameters like weight, length, and head circumference of babies. Two milliliters of umbilical venous blood were obtained to study platelet parameters and MPV levels.
There was statistically significant increase in MPV (p <.05) in IDM as compared with control group.
MPV is useful for representing the potential oxidative stress of IDM. The mean platelet volume and other platelet parameters may significantly aid in identification of diabetic pregnants at risk for vascular complications.
Cord blood, Gestational diabetes mellitus, Mean platelet volume, Morbidity, Oxidative stress
