1Assistant Professor, Dept of Physiology, Kodagu Institute of Medical Sciences, Madikeri, Karnataka
2Professor, Dept of Physiology, Koppal Institute of Medical Sciences, Koppal, Karnataka
3Professor, Dept of Physiology, Navodaya Medical College, Raichur, Karnataka
*Corresponding author: Vijayanath Itagi Professor, Dept of Physiology, Koppal Institute of Medical Sciences, Koppal, Karnataka, E-mail: Vijainath itagi, dritagi@gmail.com
Online published on 4 April, 2019.
T2DM often have both quantitative and qualitative abnormalities of lipoproteins that are responsible for increased incidence of microvascular and macrovascular complications. Incidence of coronary heart disease is three to four folds higher in patients with type 2 diabetes mellitus compared to non diabetics. It has been proposed that the composition of lipid particles in diabetic dyslipidemia is more atherogenic than other types of dyslipidemia.
Evaluate the changes in lipid profile level in diabetes and non diabetic patients.
This study was conducted on 100 subjects (50 T2DM patients with history more than ten yrs diabetes and 50 non diabetic control) with the age group of 40–60 yrs. Fasting plasma glucose and different Lipid fractions were estimated using standard procedure. All values were expressed as mean ± S.D. Statistical significance of differences between control and study groups were evaluated by student's t test. A p-value less than 0.05 were considered as significant.
The serum total cholesterol, LDL cholesterol and triglycerideswere significantly raised where as the level of HDL cholesterol was significantly lower in diabetic subjects as compared to control.
Dyslipidemia is a common finding among DM patients. DM patients should be screened and appropriate management should be instituted to reduce the risk of CHD and atherosclerosis.
Diabetes, Lipid Profile, Dyslipidemia
