International Journal of Physiology

  • Year: 2019
  • Volume: 7
  • Issue: 2

Assessment of Bronchomotor Tone in Normal and Overweight/Obese Normal Subjects

  • Author:
  • Hari Mohan Prasad Sinha1,, Bipin Bihari Pradhan2, Arsalan Moinuddin1, Ashish Goel3, Rajesh Misra4, Manisha Gupta5, Sukhmani Saini1
  • Total Page Count: 6
  • Page Number: 17 to 22

1Assistant Professor, Department of Physiology, Shridev Suman Subharti Medical College, Dehradun, Uttarakhand

2Professor, Department of Physiology, SCB Medical College, Cuttack, Orissa

3Associate Professor, Department of Physiology, Shridev Suman Subharti Medical College, Dehradun, Uttarakhand

4Professor, Department of Physiology, Shridev Suman Subharti Medical College, Dehradun, Uttarakhand

5Professor, Department of Physiology, Saraswathi Institute of Medical Sciences, Hapur, UP

Abstract

Obesity in children and young adults is on a stupendous rise over the last decade globally making the individual highly susceptible to various diseases. Pulmonary functions are well reported complications of obesity in adults with reduced lung volume & expiratory flow rates being the most frequent reported abnormalities.

This cross sectional analytical study was undertaken in the research lab of the Department of Physiology, M.K.C.G. Medical College over a period of 12 months on 300 students to determine baseline anthropometric measurements and pulmonary function tests using spirometry. Independent ‘t’ test and multiple linear regression in SPSS 20.0 is used to statistically ascertain the aforementioned objective stated in the background.

VC, ERV, TV, dynamic pulmonary functions; FEV1, MEF25along with PIF and MIF50 showed statistically significant decline in overweight/obese individuals. The aforementioned findings of VC, ERV &FEV1 showed a similar diminished trend in overweight/obese individuals on further evaluation using multiple linear regression analysis.

Overall most of the pulmonary functions tests showed compromised status in overweight/obese individuals with VC, ERV, TV, FEV1, MEF25, PIF and MIF50 exhibiting statistically significant reduction. Mechanistically, this can be attributed to the presence of adipose tissue around the rib cage, in the abdomen and visceral cavity loading the chest wall leading to small airway collapse and subsequent lowering of pulmonary function tests.

Keywords

Pulmonary function test, Obesity,