International Journal of Physiology
  • Year: 2019
  • Volume: 7
  • Issue: 2

High Sensitivity C Reactive Protein: A Surrogate Marker Appalling the Impact of Inflammation in Obese Young Adults

1Assistant Professor, Department of Physiology, Government Vellore Medical College & Hospital, Adukkamparai, Vellore

2Assistant Professor, Madras Medical College in Chennai

3Professor, Sri Lakshmi Narayana Institute of Medical Sciences in Pondy

4Professor, Government Vellore Medical College in Vellore

*Corresponding Author: Dr. R. Hemavathy MD, Assistant Professor, Department of Physiology, Government Vellore Medical College & Hospital, Adukkamparai, Vellore, 11, TamilNadu. Email id: rhbnithin@gmail.com

Online published on 20 July, 2019.

Abstract

Obesity is primarily considered to be a disorder of energy balance, and it has recently been suggested that some forms of obesity are associated with chronic low-grade inflammation. Obesity is a chronic, multifactorial and complex disease which poses a major public health issue increasing the risk of non-communicable diseases like, Type-2-DM, Cardiovascular disease, Hypertension etc.

The present study aims to emphasize the burden of obesity in inflammation by associating with elevated levels of hs CRP in adults.

The study was a Hospital based cross sectional study including 30 obese individuals in the age group of 17–30 years, (15 males and 15 females)with BMI > 30 were included. Other systemic diseases were excluded. Assessment was done by Weight, Height, BMI by Quetelet index and measurement of hs CRP by Immunoturbidometer. The results were tabulated and analysed.

Total of 30 obese subjects were included of which 15 were males and 15 were Females. In obese subjects hs-CRP was elevated significantly. The level of hs-CRP was proportionally elevated in relation to BMI in obese subjects.

Elevated hs-CRP levels in obese individuals indicates a proinflammatory state. This further concludes a risk for metabolic and cardiovascular manifestations in obese individuals.

Keywords

BMI, hs CRP